Poster Presentations

Marco Franza
Improvement in Inhalation Technique During a Pharmacy-Led Connected Inhaler Service Evaluation in Adults with Asthma or Chronic Obstructive Pulmonary Disease
Goncalo Farias
Evaluation of Regional Deposition in 3D Printed Infant Nasal Cast Models for Vaccination via Intranasal Delivery
Goncalo Farias
Human Factor Studies and Actuation Force in Multidose Nasal Pumps 
Sana Hosseini
A Spray-Drying Framework for Intranasal Powders Across Multiple Sites and Dryer Scales
Sana Hosseini
From Droplets to Particles: Excipients Shaping Spray‑Dried Intranasal Powders
Benjamin Thorne
Simulating In Vitro Aerosolization Performance: A Tool to Support Valve Selection for Suspension Pressurized Metered Dose Inhaler Products
Shaun Williams
Decarbonizing the Pressurized Metered Dose Inhaler Valve: Designing a Low-Carbon Valve for the Next Generation of Pressurized Metered Dose Inhalers
CGT Pharma Consulting
Stephen Stein
A Simple Calculation to Provide Insight into Impact of Propellant on Spray Pattern
CGT Pharma Consulting
Stephen Stein
Seventy Years of Metered Dose Inhalers
Croda
Veronica Freitas Blanco
Evaluation of Permeation Enhancers for Intranasal Delivery of Epinephrine and Naloxone Hydrochloride Using a 3D Nasal Tissue Model
Eastern Institute of Technology
Tingting Shi and Yuqing Ye
Development and Characterization of Inhalable Microparticles Co-Delivering Nintedanib and Metformin for Idiopathic Pulmonary Fibrosis
Navid Monshi Tousi and Jan De Backer
In Silico Evaluation of Nasal Spray Plume Angle and Ovality: Effect on Regional Nasal Deposition
Hosein Sadafi and Jan De Backer
Using Rapid Deposition Analysis and Realistic Aerodynamic Particle Size Distribution Variability to Support In Silico Bioequivalence Assessment
Gradient
Isaac Mohar
Leachables Toxicological Risk Assessment: Read-Across Case Study of Permissible Daily Exposure Limit Derivation for Butyl Oligomer (C21H40)
Marian Asch and Rui Alberto Teixeira Cruz
Screening of Capsule-Filling Process Parameters in the Development of Spray-Dried Powder Products for Pulmonary Delivery
Irene Rossi
In Vitro Performance Assessment of Fluticasone Propionate/Salmeterol Xinafoate Blends Developed for a Capsule-Based Device
Irene Rossi
In Vitro Performance of a Mannitol-Based Spray-Dried Powder Combined with Quattrii Carrier Free Dry Powder Inhaler
Healthy Airways
Loy Britto
Evaluation of Albuterol Sulfate Formulations with Low Global Warming Propellants using a Non-PFAS-Coated MDI Can
Angelo Araujo and Claudia Costa
Advancing Nasal Powder Delivery: A Structured Evolution of Device Performance
Claudia Costa
Evaluation of β-lactoglobulin (Dispersome®) as a Novel Excipient for Pulmonary and Nasal Delivery
Beatriz Gamelas and Dina Morais
Critical Quality Attribute-Driven Calu-3 Air-Liquid Interface Model for Comparative Permeability Screening of Dry Powder and Liquid Formulations  
InformiX Pharma
Parmesh Gajjar and Darragh Murnane
Determining Material Composition of Fines-Only Formulations Through X-Ray Computed Tomography
Inhalon Biopharma
Ellen Farmer
Stability and Aerosol Characterization of ACE-2 Decoy Antibody Delivered by a Vibrating Mesh Nebulizer
Anna Vivani and Irene Rossi
Preliminary Spray Drying Screening Study for the Reformulation of Ganaxolone from Oral to Nasal Delivery
Svetlana Lyapustina and Sheryl Johnson
Managing Supply Continuity During the Pressurized Metered Dose Inhaler Transition to Next Generation Propellants
Svetlana Lyapustina and Beatriz Noriega Fernandes
The Case for Inhaled, Thermostable Powder Vaccines Against Respiratory Pathogens in Pandemic Readiness
Johannes Gutenberg-Universität Mainz
Moritz Fleischhauer
Single Jet Impaction as an Alternative Mechanism for Soft Mist Generation
Donovan Yeates
A Programmable Aerosol Delivery Platform with Multi-Formulation Capability and High Aerosolization Rates
Rob McCorkle
Tuning Nasal Spray Performance by Formulation Design
Katherine Polzin
Assessment of Dissolution Profiles for Mometasone Furoate Inhalers Using a Paddle-Over-Disk Dissolution Apparatus
Keith Ung
Design of Spray-Dried Glucagon-Like Peptide-1 Exenatide Microparticles for Pulmonary Delivery: A Room-Temperature Stable Formulation of an Oxidation Sensitive Peptide
Keith Ung
Recording and Analysis of Healthy Subjects Breathing Maneuvers with an AdheResp Breath-Actuated Nebulizer
Ken Lo
Powder Rheology for Batch Comparison During Manufacturing
Adam Schneiderhan and Beatriz Fernandes
Excipient Effects on Spray-Dried Antibody Stability: A Comparative Study
Luxena Pharmaceuticals
Xiaodong Li
Ondansetron Inhalation Powder: Bioavailability and Safety Results from Phase 1 Clinical Study
Vaishnavi Kapileshwari and Mridul Majumder
Morphological Characterization of Dry Powder Inhaler Formulations: A Reaction to the US Food and Drug Administration Guidelines
Monash University
Edward Attenborough
Medium Chain Length Polyhydroxyalkanoate Nanoparticles for Controlled Drug Delivery to the Lung
Ben Miles and Lucas Silva
Predicting Nasal Deposition from Minimal In Vitro Data with Machine Learning
CC
Nitto BioPharma
Cima Cina and Wendy Knowlton
Inhalation and Systemic Delivery of mRNA to the Lung Using a Stable Lipid Nanoparticle Platform
Orexo AB
Jonas Sävmarker
Thermostable Powder-Based Nasal Vaccine: Preclinical Evaluation of Immunogenicity and Stability
David Lewis
Defining a Reproducible Reference Condition for 'Immediate' Actuation in Low-Global Warming Potential HFA-152a Albuterol Sulphate Suspension Pressurized Metered Dose Inhalers
Murat Ali
Development of a Connectivity Module for an Open-Inhale-Close Device That is Both Patient-Centric and Non-Intrusive to Dry Powder Delivery
Carolina Dantas and Ulf Krueger
Predicting Pulmonary Drug Deposition Using Real-Time Connected Inhalation Data
Nicolas Buchmann
Actuation and Viscosity Dependent Aerosol Generation in Nasal Sprays: A Mechanistic Comparison of Swirl Nozzle and Soft Mist Technologies
RTI International
Sara Maloney Norcross
Replacing Sugar Excipient with Polymyxins to Improve Dosing of a Dry Powder Teixobactin-Lipopeptide Hybrid for the Treatment of Pulmonary Infections
RTI International
Erik Pena and Sara Maloney Norcross
Optimization of Spray-Dried Spectinamide Lee1810 Inhalation Powders
Erik Boldt
Antimicrobial Effectiveness Testing of HFO-1234ze(E) with and without Ethanol
Erik Boldt
Minimizing Variability in Shot Weight of HFO-1234ze(E) Metered Dose Inhalers Using Automated Systems Compared with Manual Handling
Gregory Smith
Budesonide Solution Formulations in HFO-1234ze(E): Novel Alternatives to Suspensions
Gregory Smith
Performance Comparison of Fluticasone Propionate Suspension Formulations in HFO-1234ze(E) to a Reference Listed Drug
Yannick Baschung
Adapting Standard Nasal Spray Testing Methodologies for Live BSL-2 Viral Products: An In-Use Case Study with a SARS-CoV-2 Nasal Vaccine
South Dakota State University
Fabius Irabin
Evaluation of Metformin Encapsulated Rod-Shaped Iron (III) Carboxylate Biomimetic NanoMetal-Organic Frameworks as Antibacterial Immunotherapy
South Dakota State University
Joshua Reineke
Characterization and Safety of Biomimetic Metal-Organic Frameworks in Macrophages
South Dakota State University
Joshua Reineke
Numerical and Experimental Studies to Enhance Nasopharyngeal Deposition by Optimizing Spray Plume Angle and Particulate Sizes for Intranasal Drug Delivery
St. John's University
Parasharamulu Kommarajula
Development and Evaluation of Inhalable Imipenem Dry Powder for Treating Pulmonary Pseudomonas aeruginosa Infections
The University of Alabama at Birmingham
Teri Ross
Particle Level Assessment of Size and Composition as a Function of Aerosol Particle Size Using Optical Photothermal Infrared Microscopy: Comparison of Fluticasone/Salmeterol/Lactose in Advair Diskus and Wixela Inhub
Mark Nagel
Can a Mixing Inlet Interposed Between a Pressurized Metered Dose Inhaler-Spacer Combination and Cascade Impactor Enable Effective Performance Testing at Widely Different Inhalation Flow Rates?
U.S. Food & Drug Administration
Bora Sul
Computational Modeling of Actuation Timing Effects on Regional Lung Drug Delivery from Pressurized Metered Dose Inhalers
U.S. Food & Drug Administration
Yang Yang and Susan Boc
Comparative Analysis of Phospholipid Porous Particle Size Distribution in Orally Inhaled Drug Products: In Vitro and In Silico Approaches
University of Bristol
Anna Catton
Rapid Stability Modeling as a Predictor for Long-Term Standard Stability Testing of Dry Powder Inhalers
University of Bristol
Sorrel Haughton
Influence of Formulation Viscosity and Surface Tension on Spray Formation and Nasal Deposition with a VP7 Nasal Valve Device
University of Hertfordshire
Hessam Rasooli Nia
Nasal Delivery of Liquid Medicines: Effect of Viscosity and Polymer Structure on Delivery Performance
University of Michigan
Grace Xia
A Distribution-Based Metric for Quantifying Dispersibility in Dry Powder Inhalers
University of Michigan
You Xu and Guizhi (Julian) Zhu
Inhalable Anti-Inflammatory psLNPs Enable Mucus Penetration and circRNA CFTR Delivery For Cystic Fibrosis Therapy
University of Michigan
Guizhi (Julian) Zhu
Airway Delivery of circRNA Using Pulmonary-Surfactant-Coated Lipid Nanoparticles for Cystic Fibrosis Gene Therapy
University of Oklahoma
Lucila Garcia-Contreras
Direct Aerosol Administration in Preclinical Respiratory Models: Influence of the Parameters of Administration Using the Fine Mist Sprayer
Francesca Buttini
Development of PEGylated DNase for Nebulization
Francesca Buttini
Engineering Budesonide Microparticles to Improve Suspension Stability in Low-Global Warming Potential Pressurized Metered Dose Inhalers 
University of Sydney
Zhengqi Xu and Dipesh Khanal
Combination of a Newly Developed Modified Next Generation Impactor and Franz Cell Method for In Vitro Dissolution Characterization of Inhalation Powders: Development and Validation
University of Sydney
Zhengqi Xu and Dipesh Khanal
Use of a Modified Next Generation Impactor and Franz Cell for Characterization of the In Vitro Dissolution Performances of Innovator and Generic Dry Powder Inhalers
Jordan Potts
Influence of L-Leucine Content on the Internal and External Morphology of Spray-Dried Particles
Federica Carnamucio
Inhalable Liposomal Combination Therapy for the Treatment of Osteosarcoma Lung Metastases
Baiwei Chen
Impact of Spray-Dryer Technology on the Aerosol Performance and Physicochemical Properties of Synthetic Dipalmitoylphosphatidylcholine Dry Powder Formulations
Caleb Dalton
Investigating Effects of Single Prong Nasal Interface Orifice Diameter and Capillary-to-Orifice Distance on Air Jet Dry Power Inhaler Plume Properties and Performance
Victoria Garcia
Studying the Pharmacodynamic Response of the Tumor Immune Microenvironment in Osteosarcoma Lung Metastases Following Inhaled Gemcitabine Treatment
Mohammad Hejazi
Device Characteristics and Orientation Effects on Regional Nasal Drug Deposition in an Anatomical Nasal Model
Mohammad Hejazi
Effect of Breathing Pattern and Emitted Dose on Regional Deposition of Soft-Mist Nasal Sprays
Mohammad Momin
Achieving Improved Lung Delivery of Synthetic Lung Surfactant Excipient Enhanced Growth Dry Powder Aerosol Formulations in Neonates
Rudra Pangeni
Tobramycin-Synthetic Lung Surfactant Dry Powder for Treatment of Pseudomonas aeruginosa-Induced Lung Infection in Rats
Surendra Poudel
PEGylated Ciprofloxacin Liposomal Dry Powder: Efficacy in Acute Rat Pseudomonas aeruginosa-Induced Lung Infection
Cimone Richardson
Pulmonary Delivery of Ginkgetin Attenuates Lung Fibrosis in a Rat Model
Riley Schweizer
Development of an Inhalation-Assisted Pediatric Dry Powder Inhaler and Synthetic Lung Surfactants Excipient Enhanced Growth Platform for Anti-Infective Aerosol Delivery
Laura Vargas
Development and Validation of a Customizable Neonatal Breathing Simulator for Aerosol Delivery Evaluation Using a Laryngeal Mask Airway Aerosol Delivery System
Western University
Ziyi Fan and Yuqing Ye
Inhaler Usage Recognition Using Transformer-Based Acoustic Modeling
Woolcock Institute of Medical Research
Patrick He
Bridging Deposition and Permeation: Evaluation of Intranasal Dry Powder Antiemetic Formulations
Dean Wang
Nebulization of Complex Formulations: A Physicochemical Property Tailored Strategy for Vibrating Mesh Nebulizers

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