Bench to Bedside

SESSION 2: From Bench to Bedside:
New Tools and Targets

Monday • May 6, 2024 • 2:00–3:00 PM • Arizona Ballroom
Moderator: John S. Patton, Ph.D.

Plenty of Room at the Surface - Inhalable Polymeric Nanoparticles for Lung Delivery
Laura Rotolo
Emory University
Development of Inhalable Ion Channel Prosthetics for Cystic Fibrosis
Jeffry Weers
cystetic Medicines

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AeroFactTM: A Clinical Path to Inhaled Surfactant Treatment for Infants and Adults
Andrew Clark and James Fink
Aerogen Pharma
Aerosolized Surfactants for the Treatment of Neonatal Respiratory Distress Syndrome: Challenges and Opportunities
Robert DiBlasi
Seattle Childrens Research Institute
A Dry Powder Route to Effective Aerosol Surfactant Therapy: A Little Can Go a Long Way
High-Content Image Analysis for Phenotypic Characterization of Foamy Macrophage Responses of Alveolar Macrophages to Amiodarone
Louis Scott and Ewelina Hoffman
ImmuONE
Impact of Vibrating Mesh Nebulization on the Physicochemical Properties of mRNA and siRNA Lipid Nanoparticle Formulations
Katrin Wiebe and Simone Carneiro
Ludwig-Maximilians-University Munich
Liposomal Formulation Reduces Cell Uptake of Bacteriophage in a Lung Epithelial Cell Model
Shruti Sawant
Purdue University
Effects of Surfactant Coating on Levofloxacin-Loaded Nanoparticles: Impact on Physicochemical Properties and In Vitro Cell Viability of Pulmonary Cells 
Laura Oliveira Nascimento
Universidade Estadual de Campinas
Enhancing Polymeric Nanodispersions for Improved Doxycycline Efficacy Against Lung Pathogen Biofilms
Victória Soares Soeiro
Universidade Estadual de Campinas
Evaluating Published Artificial Mucus Models for Understanding Predictability of Inhaled Drug Delivery Dynamics
Nishant Shah
University of Michigan
Efficacy of Inhaled ALX1 in a Model of Chronic Pseudomonas Aeruginosa Infection
Mark Schoenfisch
Vast Therapeutics
Locally Administered Gemcitabine Chemotherapy for the Treatment of Osteosarcoma Lung Metastases
Designing mRNA Lipid Nanoparticles for Tumor Associated Macrophages: Towards Immunotherapies for the Treatment of Osteosarcoma Lung Metastases
A Novel Hybrid Molecule of Melatonin and Curcumin: In Vivo Therapeutic Intervention in the Rat Model of Lung Fibrosis with Local Lung Delivery
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