Posters on the Podium

Posters on the Podium

Thursday • May 8, 2025 • 10:30–12:00 Noon
Moderators: Daniela Traini, Ph.D., Macquarie University & Woolcock Institute, Sydney, Australia and
Patricia Henriques, Ph.D., Hovione, Lisbon, Portugal

Design, Development, and Validation of a Novel Dry Powder Inhaler Adaptor for Increased Deposition of Anti-Inflammatory Agents in Pediatric Asthma
Lily Zhu
Johns Hopkins University
A Comparison of Particle Dynamics within Several Airway Models using Phase Doppler Anemometry
Peter Di Palma
University of Toronto
Effects of Airway Wall Dynamics During Inhalation on Drug Delivery via Pressurized Metered Dose Inhalers Using Patient-Specific Airway Models
Mahsa Jahed
Lakehead University
Optimizing Intranasal Delivery of Peptides for Targeted Brain Drug Delivery in Transgenic Mouse Models of Alzheimer’s Disease
Chun Yuen Jerry Wong
Macquarie University & Woolcock Institute
Lactobacilli Inhalation Powders as Antibacterial Agents against S. Aureus
Stefania Glieca
University of Parma

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Impact of a Digital Health Respiratory Disease Management Platform on Adult Asthma
Akash Bijlani
Aptar Digital Health
Meta Analysis of Variables Affecting Nasal Spray Product Actuation Force Profile
Goncalo Farias
Aptar Pharma
Development of Albuterol Sulfate pMDI using a Low Global Warming Potential Propellant 1,3,3,3-Tetrafluoropropene (HFO-1234ze) to Match Ventolin® HFA Inhaler: I. Formulation, Container Closure System and Actuator Selection Considerations
Lei Mao and Ross Errington
Bespak
Mapping the Product Design Space: Understanding and Controlling Manufacturing Variability in Pressurized Metered Dose Inhalers
Karl Bass
Bespak
Development of Albuterol Sulfate pMDI Using a Low Global Warming Potential Propellant 1,3,3,3-Tetrafluoropropene (HFO-1234ze) to Match Ventolin® HFA Inhaler: II. Human Factors Engineering Considerations
Lei Mao and Ross Errington
Bespak
High Delivered Dose in a Single Inhalation for Carrier-Based Formulations by Retaining Carrier-Fraction in Dry Powder Inhaler Blister
Heather Jameson
Cambridge Healthcare Innovations
Further Exploration on the Manufacturing Repeatability and the Interaction Between Blending Parameters of Dry Powder Blends Produced by Resonant Acoustic Mixing
Cristina Rey Blanes
Chiesi
Formulation Study on siRNA-LNP Embedded in an Inhalable Freeze-Dried Matrix for Lung Targeting
Michael Vernizzi
Chiesi Farmaceutici
Impact of Lactose Carrier Morphology and Amorphicity on the Aerosol Performance of Fluticasone Propionate Dry Powder Inhalers
Ross Blezard
DFE Pharma
Poly (ADP-Ribose) Polymerase Inhibition as a Treatment Option for Pulmonary Fibrosis
Rob Bischof
Federation University
Validation of Lung Deposition of Fluticasone Propionate/Formoterol Fumarate in Chronic Obstructive Pulmonary Disease Patients Using Functional Respiratory Imaging
Ana Costa and Hosein Sadafi
FLUIDDA
From Healthy to Diseased: Evaluating Bioequivalence in Orally Inhaled Drug Delivery
Hosein Sadafi
FLUIDDA
Sensitivity Analysis of Inhaled Drug Deposition Delivered via Metered Dose Inhalers in Chronic Obstructive Pulmonary Disease Patients
Hosein Sadafi
FLUIDDA
Impact of Anatomical Variability on Nasal Deposition in Pediatric Subjects of the Same Age and Gender
Navid Monshi Tousi and Hosein Sadafi
FLUIDDA
Investigation of In Vitro Techniques for Evaluating Ipratropium Bromide Formulations
Ameet Sule
H&T Presspart
Performance Comparison of Beclomethasone, Formoterol, and Glycopyrronium Solution Formulations in HFO-1234ze(E) to Reference Listed Drugs
Gregory Smith
Honeywell
Characterization Study of Nasal Deposition Targeting the Central Nervous System
Claudia Costa
Hovione
Distinct Baseline Phenotypical and Functional Properties of Macrophages Derived from Two Different Lots of THP-1 Monocytes for Screening the Effects of Inhalable Drugs
Alexandre Ribeiro and Mykaella Mestre
Hovione
Advancing High-Dosage Dry Powder Inhaler Formulations: Integrating Quality by Design for Optimized Performance
Rui Churro
Hovione
Optimizing Inhalation of a Monoclonal Antibody: Transitioning from Nebulization to a Dry Powder Inhaler
Luis Marques
Hovione
Aerosolization of Wegovy® and Prototype Formulations of Semaglutide with the MRX004 Soft Mist Inhaler
Mark Parry
Intertek Melbourn
Preliminary Development of a Nanostructured Nasal Powder for Nose-to-Brain Delivery of a Neuro-Active Steroid
Anna Vivani
INTO
Optimization of Carrier Particle Geometry for Enhanced Inhalation Performance by Parametric Design
Melvin Wostry
Kiel University
Understanding Drug Deposition in USP and OPCM Throats for HFA-152a Solution pMDIs
Aaron Taylor
Kindeva
An Evaluation of Extractable Levels from Various Polybutylene Terephthalate Suppliers in the Presence of Ethanol in Formulations Containing HFA-152a and HFO-1234ze
Oliver Ingham
Kindeva
Enhancing the Efficiency of pMDIs Through an Innovative Mesh Grid Design
Mona Mohammadkhani
Lakehead University
Selection of the Best Capsule Type to Maximize the Performance of a Model Carrier-Based Dry Powder Inhalation Formulation
Camille Dumont
Lonza
Fine-Tuning Spray-Dried Inhalable Powders: Impact of Component Saturation on Performance
Beatriz Noriega Fernandes and Emily Osborne
Lonza
Spray-Dried Lipid Nanoparticles for Intranasal Delivery
Cameron Kadleck
Lonza Bend
Inhalable Spray-Dried Lipid Nanoparticles for Pulmonary siRNA Delivery
Leonie Deßloch
Ludwig-Maximilians-University Munich
The Role of Carrier Particle Size in Adhesive Mixtures for Inhalation
Kyrre Thalberg
Lund University
Predicting Blend Performance of a Dry Powder Inhalation Formulation Using Raman Spectroscopy
Vaishnavi Kapileshwari and Mridul Majumder
M2M Pharmaceuticals
Experimental Investigation of the Air and Droplet Dynamics of a Soft Mist Inhaler
Michael Pangestu and Nicolas Buchmann
Monash University
Ultrasonically Actuated Platform Integrating a Drug-Loaded Cartridge with Microfluidics: Delivering High-Viscosity Solutions with Adjustable Flow Rates
Tuncay Alan
Monash University
Assessment of the Semi-Automatic Filling of UDS-P Device with Engineered Powders for Nasal Delivery
Reanne Beaird
Nanopharm, an Aptar Pharma Company
The Impact of Excipients and Spray Drying on Improving the Permeability of Spray-Dried Leuprolide Formulations Using RPMI-2650 Cells
Lucas Silva
Nanopharm, an Aptar Pharma Company
The Impact of Orbital™ Device Puck Configurations on the Deposition of Itraconazole
Lucas Silva
Nanopharm, an Aptar Pharma Company
A New Nebulizer Architecture Using Coupling Layer-free Superstrates Allows Easier Cleaning and Better Performance Over Time
David Tatnell
Nebu~Flow
An Acoustic Nebulizer Platform for Aerosolization of Biologics
Kiing Seng Wong
Nebu~Flow
Novel Method for Sized Aerosol Sampling in the Characterization of Nebulized Biologics
Sarina Saeidi
Nebu~Flow
An Assessment of the Potential Manufacturing Scale Flammability of Low Global Warming Potential Formulations
Steve Flaherty
Orbia Fluor & Energy Materials
Assessment of Suspension Characteristics of Budesonide Micronized by Traditional Jet Milling and by Sonocrystallization Suspended in High and Low Global Warming Propellants
James Murray
Orbia Fluor & Energy Materials
Novel Spray-Dried Nasal Powder of Eletriptan: In Vitro and Pre-Clinical In Vivo Studies
Jonas Sävmarker
Orexo AB
Plume Temperature: HFA-134a & HFA-227ea Compared to Low GWP Propellants HFA-152a & HFO-1234ze
David Lewis
Oz-UK Limited
Correlation of Leakage and Aerosol Performance Measurement for Five Valved Holding Chambers with Pediatric Facemasks
Andrea Winzen
PARItec
Simplified Mechanism Modelling: Optimizing a Dry Powder Inhaler for Ease of Use
Philip Smith
Phillips Medisize
The Importance of Shear Thinning for High Viscosity Nasal Suspensions
Summer Hancock
Phillips Medisize
Advancing Cleaning and Disinfection Standards for Mesh Nebulizers: A Patient-Centric Study Introducing Zerowater®
Iain Ross
Phillips Medisize
The Influence of Freezing, Storage, and Formulation on Mannitol Polymorphism and Powder Deposition after Spray Freeze-Drying
Lorena Pasero
Politecnico di Torino
Spray Freeze-Drying Inhalable Powders of a Monoclonal Antibody: The Role of Formulation in Achieving Stability and Flowability
Lorena Pasero
Politecnico di Torino
Modelling the Impact of Mucoadhesive Formulations on Intranasal Delivery of RIG-101, a Stem-Loop Ribonucleic Acid Therapeutic
Jag Shur
RIGImmune
Refining Regional Deposition Predictions in Metered Dose Inhalers: A Comparison of Static and Dynamic ICRP Models
Jag Shur
RIGImmune
Evaluating Critical Handling Errors in Inhalation Devices: The Role of Tailored In Vitro Testing
Yannick Baschung
Solvias
Development of a Particle Engineered Aspirin Powder for Intranasal Delivery: Evaluating Delivery Performance from a Novel Intranasal Device
Julie-Ann Penton
Therakind
Clinical Evaluation of a Prototype Smart Valved Holding Chamber to Monitor and Improve Adherence to Metered Dose Inhaler Medication
Jason Suggett
Trudell Medical International
Inhaled Maintenance and Reliever Therapy and Anti-Inflammatory-Reliever Therapy: Exploring In Vitro Performance of a Portable Valved Holding Chamber
Mark Nagel and Jolyon Mitchell
Trudell Medical International
Assessing Fitness-for-Purpose to Support Clinical Application of an Adaptive Breath-Actuated Nebulizer
Lois Slator
University of Hertfordshire
Development of a Single Actuation Impaction Method for Aerosolization Assessment of Soft Mist Inhalers: Comparison for MRX004 and Respimat®
Giorgia Vaccaro and Darragh Murnane
University of Hertfordshire
Pre-Actuation Microstructure within Dry Powder Inhaler Blisters Revealed Through X-Ray Computed Tomography
Darragh Murnane
University of Hertfordshire
Influence of Viscosity and Surface Tension on Droplet Size Distribution and Plume Characteristics of the Respimat® Soft Mist Inhaler
Benjamin Mignot
University of Leeds
Development of a Dry Powder Formulation of Deoxyribonuclease I using Spray Drying
Aoife Cotter
University of Limerick
Bulk Excipient Screening of a Spray Dried Glucagon-Like Peptide 1 Receptor Agonist Formulation
Stefania Glieca and Irene Rossi
University of Parma
Leveraging Chemo-Immunotherapy to Remodel the Tumor Microenvironment and Enhance Treatment Efficacy in Osteosarcoma Lung Metastases
Raneem Aldaqqa
Virginia Commonwealth University
In Vivo Deposition and Retention of Ciprofloxacin Liposomal Dry Powder Aerosol
Rudra Pangeni and Michael Hindle
Virginia Commonwealth University
Evaluation of the Resyca® PFSI™ Soft Mist Inhaler for Efficient Delivery of mRNA-lipid Nanoparticles to the Lungs
Patrick He
Woolcock Institute of Medical Research
Comparison of Solution and Suspension Nasal Spray Formulations by Laser Diffraction and Next Generation Impactor Methods
Gözde Fidan and Sulenur Ekmekci
World Medicine
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