SESSION 3: Posters on the Podium
Monday • May 6, 2024 • 3:30–5:00 PM • Arizona Ballroom
Moderators: Daniela Traini, Ph.D. and Elizabeth R. Bielski, Ph.D
Poster authors chosen by the Editorial Team present their work during a fast-paced podium session.
Accelerated Stability and Aerosol Performance Assessment for a Spray Dried Nasal COVID-19 Vaccine Candidate
John Chen
Access to Advanced Health Institute
Access to Advanced Health Institute
Designing mRNA Lipid Nanoparticles for Tumor Associated Macrophages: Towards Immunotherapies for the Treatment of Osteosarcoma Lung Metastases
Raneem Aldaqqa
Virginia Commonwealth University
Virginia Commonwealth University
Evaluating Published Artificial Mucus Models for Understanding Predictability of Inhaled Drug Delivery Dynamics
Nishant Shah
University of Michigan
University of Michigan
Enhancing Nose-to-Brain Drug Delivery: A Comparative Study of Peptide Formulations Using a Multidose Nasal Spray
Chun Yuen Jerry Wong
Macquarie University
Macquarie University
Tuning the Aerosol Delivery of the Respimat® Soft Mist Inhaler
Moritz Fleischhauer
Johannes Gutenberg-Universität Mainz
Johannes Gutenberg-Universität Mainz
Measurement of Vapor Pressure and Viscosity of Ethanol in HFA134a, HFA152a, and HFO1234ze(E) Mixtures used in pMDIs
Swetha Chowdary Vutlapalli and Daniel Duke
Monash University
Monash University
Optical Photothermal Infrared Spectroscopic Assessment of Fluticasone/Salmeterol/Lactose Co-Association in Advair Diskus® and Wixela Inhub®
Dipesh Khanal
University of Sydney
University of Sydney
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Optimization of a Multidose Nasal Actuator Targeting Olfactory Region Deposition
Goncalo Farias and Charles Cazzola
Aptar Pharma
Aptar Pharma
Leachables Assessment from a New Generation of pMDIs using Low Global Warming Potential Propellants and the Impact of Ethanol Filling
Pauline Faucard and Benedicte Grosjean
Aptar Pharma
Aptar Pharma
Development of Albuterol Sulfate Pressurized Metered Dose Inhalers using a Low Global Warming Potential Propellant 1,1-difluoroethane (HFA152a)
Lei Mao
Bespak
Bespak
Development of Beclomethasone Dipropionate Pressurized Metered Dose Inhalers using a Low Global Warming Potential Propellant, 1,3,3,3-tetrafluoropropene (HFO1234ze)
Lei Mao
Bespak
Bespak
Investigating the Impact of Device Design and Propellant Choice on the Aerosolization of Fluticasone Propionate Suspensions in HFA152a and HFO1234ze
Benjamin Thorne
Bespak
Bespak
Using Human Factors Studies to Optimize Nozzle Geometry for Patient Interaction in the Design Development of a Unit Dose Nasal Spray
Sabrina Falloon
Bespak
Bespak
Aerodynamic Characteristics of Spiriva® Handihaler® at Simulated Breathing Patterns of COPD and Healthy Subjects, and at a Constant Inhalation Flow using One Capsule per Determination
Jufang Xu
CF PharmTech
CF PharmTech
Designing a Sustainable Ipratropium HFA-152a pMDI: Actuator Geometry Considerations
Ameet Sule
H&T Presspart
H&T Presspart
Advancing DPI Technology: A Modular Approach on Optimizing Capsule Movement for Improved Performance
Mirjam Kobler
H&T Presspart
H&T Presspart
Ellipta® Blister Device: A Re-Assembly Set of Tools for Early In Vitro Comparative Studies of a Complex Pre-Metered Dry Powder Inhaler
Irene Rossi
Harro Höfliger Verpackungsmaschinen
Harro Höfliger Verpackungsmaschinen
Two Isn’t Always Better Than One: A Single-Actuation Salbutamol Sulfate Metered Dose Inhaler Using Low-GWP Propellant HFO-1234ze(E)
Erik Boldt and Gregory Smith
Honeywell
Honeywell
Understanding Leucine Encapsulation in Dry Powder Inhaler Microparticles via Surface Characterization Techniques
Lidia Santos and Claudia Costa
Hovione
Hovione
Differential Permeability of Dry Solid and Aqueous Suspensions of Fluticasone Propionate Through A549 Alveolar Epithelial Cells
Alexandre Ribeiro
Hovione
Hovione
Drug Load Influence on Aerodynamic Properties of High Dosage DPIs: A Case Study of an Aminoglycoside Model Drug
Maria Ines Lopes and Joao Pires
Hovione
Hovione
Systemic Nasal Absorption of Amorphous Solid Dispersions: Supersaturating Systems for Fast Onset of Action of Poorly Soluble Drugs through the Nasal Mucosa
Patricia Henriques and Dina Morais
Hovione
Hovione
Novel Inhaled Anti-Viral Against SARS-CoV-2: Feasibility of Developing a Nanofitin Dry Powder Formulation for Pulmonary Delivery using the ICOone Single Dose Dry Powder Inhaler
Måns Österberg Widerstrand and Jakob Samsøe
Iconovo
Iconovo
The Impact of the Universal Spacer System on Efficiency and Reliability of Dose Delivery of Inhaled Nebulized Aerosols
Barry Clements
Inspiring Holdings Pty Ltd
Inspiring Holdings Pty Ltd
Laser Diffraction Size Analysis of Products for Nasal Inhalation: A Survey of Expert Users
Jolyon Mitchell
IPAC-RS
IPAC-RS
Regulatory Topics in Nasal Product Development: Pediatrics and Reliability Expectations
Svetlana Lyapustina
IPAC-RS
IPAC-RS
Practical Considerations for Conducting Successful In Vitro Bioequivalence Studies on Inhalers
James Drake
Kindeva Drug Delivery
Kindeva Drug Delivery
Formulation of an Intranasal Dry Powder Vaccine Candidate for Tuberculosis
Sana Hosseini and Kimberly Shepard
Lonza
Lonza
Manufacturability of Intranasal Dry Powders Spray Dried from Aqueous Solutions
Neerja Zambare and Kimberly Shepard
Lonza
Lonza
Application of Raman Spectroscopy for Dry Powder Inhalation Formulation
Mridul Majumder
M2M Pharmaceuticals
M2M Pharmaceuticals
Utilizing Physiologically-based Modeling for the Design of an Inhaled Powder Formulation of Imipenem Aimed at Maximizing the Dose Delivered to the Lung Lining Fluid
Will Ganley
Nanopharm, an Aptar Pharma Company
Nanopharm, an Aptar Pharma Company
Comparative Assessment of Plume Velocity in pMDI Solutions: A Study using Phase Doppler Anemometry and SprayView Analysis
Will Ganley and Nuria Manzano
Nanopharm, an Aptar Pharma Company
Nanopharm, an Aptar Pharma Company
Case Studies on Reformulation of BDP MDIs using Low GWP Propellants HFO1234ze and HFA152a
Daniel Lewis
Oz-UK Limited
Oz-UK Limited
Aerosol Performance and Usability Evaluation of New Pediatric Facemasks for a Valved Holding Chamber
Andrea Winzen and Martin Schlun
PARItec
PARItec
Inhalation and Exhalation Airflow Resistance of Valved Holding Chambers
Deborah Jones and Timothy Fallon
Proveris Scientific
Proveris Scientific
Methodology for Measurement of Evaporation Fraction and Evaporation Rate: A Comparison of HFA-134a and HFA-152a pMDI Formulations
Lynn Jordan
Proveris Scientific
Proveris Scientific
Examining User Breathing Patterns During Nebulization with a Guided Inhalation Maneuver
Carolina Dantas
Pulmotree Medical
Pulmotree Medical
Effect of Flow Rate on Emitted Aerodynamic Particle Size Distribution from a Dry Powder Inhaler Delivering a Short-Acting Beta2 Agonist as Monotherapy
Mark Nagel
Trudell Medical International
Trudell Medical International
Successful Scale-Up of a Spray Dried Formulation for Nasal Drug Delivery
Lara Penn
Upperton Pharma Solutions
Upperton Pharma Solutions
Exploration of Alternative Methodologies for Spray Pattern Evaluation in a Budesonide/Formoterol Fumarate Dihydrate pMDI
Fraser Carr
Vectura
Vectura
A Novel Hybrid Molecule of Melatonin and Curcumin: In Vivo Therapeutic Intervention in the Rat Model of Lung Fibrosis with Local Lung Delivery
Masahiro Sakagami
Virginia Commonwealth University
Virginia Commonwealth University
Efficient Delivery of Powder Aerosol to the Lungs of Small Animals with a New Air-Jet Dry Powder Insufflator
Rudra Pangeni
Virginia Commonwealth University
Virginia Commonwealth University
Advancements in Complete-Airway Modeling of Pharmaceutical Aerosols: Implementation of a Tracheobronchial Voluming-Filling Algorithm
Morgan Thomas
Virginia Commonwealth University
Virginia Commonwealth University
Locally Administered Gemcitabine Chemotherapy for the Treatment of Osteosarcoma Lung Metastases
Victoria Garcia
Virginia Commonwealth University
Virginia Commonwealth University
In Vivo Efficacy of Tobramycin Excipient Enhanced Growth Dry Powder Aerosol in Pseudomonas Aeruginosa Lung Infection Model
Surendra Poudel
Virginia Commonwealth University
Virginia Commonwealth University
Comparison of In Vitro Aerosol Performance and Powder Characteristics of a Synthetic Lung Surfactant Powder Aerosol Formulation Produced using Two Spray Drying Methods
Felicia Hall
Virginia Commonwealth University
Virginia Commonwealth University
Pharmaceutical Aerosol Deposition in a Stainless-Steel Version of the VCU Mouth-Throat Models
Caleb Dalton
Virginia Commonwealth University
Virginia Commonwealth University
Spray Characterization of Low Volume Air-Jet Dry Powder Inhaler Devices for the Delivery of a Synthetic Lung Surfactant Powder Formulation
Caleb Dalton
Virginia Commonwealth University
Virginia Commonwealth University